Longevity & Cellular

NMN 500

500mg pharmaceutical-grade NMN per capsule — the direct NAD+ precursor that restores the cellular energy and DNA repair capacity of a younger biological state.

$79 60 capsules · 30-day supply

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NAD+ is the molecule your cells use to produce energy via mitochondrial ATP synthesis. By your 40s, NAD+ levels have dropped 30–50% from peak — taking with them your energy production, DNA repair capacity, and metabolic regulation. You feel this as slower recovery, reduced cognitive sharpness, and an invisible ceiling on output you cannot train your way past.

NMN is the most direct and bioavailable NAD+ precursor available. Unlike NR, NMN is taken up directly by cells via the Slc12a8 transporter and converted to NAD+ within minutes. Our 500mg dose reflects the protocol used in the primary published human trials demonstrating significant NAD+ elevation — not the 125–250mg under-doses common in commercial products formulated for margin, not efficacy.

"NAD+ participates in over 500 enzymatic reactions. It is not one molecule among many — it is the metabolic currency your cells spend on every process that keeps you functional."

The Sanctum System

Where It Fits

NMN is the cornerstone of the Longevity & Cellular tier. It works upstream of everything else — by raising NAD+ levels, you improve the efficiency of every other compound you take. Stack with Shilajit Resin (fulvic acid enhances mitochondrial NAD+ utilization) and K2+D3 for a complete cellular longevity foundation.

Daily Stack · Longevity & Cellular

Built For

Who It's For

Anyone over 35 who wants to preserve and restore metabolic function at the cellular level. NMN is the compound longevity researchers take themselves. It is not a marketing story — it is a direct intervention in one of the most well-documented biochemical mechanisms of biological aging.

You are 35+ and noticing an energy floor drop that training doesn't resolve
You want to maintain cognitive performance as you age
You are optimizing for longevity, not just short-term performance
You are running a comprehensive daily supplement protocol

Formulation

What's Inside

Compound	Amount Per Serving	Role
Nicotinamide Mononucleotide (NMN)	500mg	Direct NAD+ precursor via Slc12a8 transporter — raises cellular NAD+ within hours of ingestion
BioPerine® (Black Pepper Extract)	5mg	Absorption enhancer — increases NMN bioavailability by up to 20%

Serving size: 2 capsules. 60 capsules per bottle. Manufactured in the USA in a cGMP-certified facility. Third-party tested for potency and purity.

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Questions

Frequently Asked

What's the difference between NMN and NR? +

Both are NAD+ precursors, but NMN is taken up directly by cells via the Slc12a8 transporter, bypassing a conversion step NR requires. In published studies, NMN shows faster plasma elevation and more direct cellular uptake at comparable doses.

When is the best time to take NMN? +

Morning, with or without food. NAD+ plays a central role in circadian rhythm regulation, and morning dosing aligns with your body's natural NAD+ production cycle.

How long before I notice effects? +

Most report increased energy and mental clarity within 2–4 weeks of consistent use. NAD+ restoration is cumulative — stay consistent for 90 days before full evaluation.

Is 500mg the right dose? +

500mg/day is the dose used in the primary published human trials showing significant NAD+ elevation. Lower doses common in commercial products (125–250mg) are formulated for margin, not the level the research actually supports.

Can I stack NMN with Shilajit? +

Strongly recommended. Shilajit's fulvic acid has been shown to enhance mitochondrial function and amplify NAD+ utilization at the cellular level. The two compounds work through complementary mechanisms and are a core Sanctum longevity pair.

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